United States securities and exchange commission logo April 24, 2023 Richard Lowenthal, M.S., MSEL President and Chief Executive Officer ARS Pharmaceuticals, Inc. 11682 El Camino Real, Suite 120 San Diego, California 92130 Re: ARS Pharmaceuticals, Inc. Registration Statement on Form S-3 Filed April 20, 2023 File No. 333-271359 Dear Richard Lowenthal: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Joshua Gorsky at 202-551-7836 with any questions. Sincerely, Division of Corporation Finance Office of Life Sciences cc: Kenneth J. Rollins, Esq.